HDAC5 (phospho Ser498) rabbit pAb

Ref. EK-ES1324

Información del producto

• Nombre: HDAC5 (phospho Ser498) rabbit pAb
• Sinónimos: HDAC5; KIAA0600; Histone deacetylase 5; HD5; Antigen NY-CO-9

Descripción

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

• Marca: ELK Biotechnology