MLK3 (Phospho Thr277+Ser281) rabbit pAb

Ref. EK-ES20162

Información del producto

• Nombre: MLK3 (Phospho Thr277+Ser281) rabbit pAb
• Sinónimos: Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25;Mixed lineage kinase 3;Src-homology 3 domain-containing proline-rich kinase)

Descripción

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008],

• Marca: ELK Biotechnology