Endothelin B Receptor rabbit pAb

Ref. EK-ES20766

Información del producto

• Nombre: Endothelin B Receptor rabbit pAb
• Sinónimos: Endothelin B receptor (ET-B;ET-BR;Endothelin receptor non-selective type)

Descripción

The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016],

• Marca: ELK Biotechnology