Calpain 10 rabbit pAb
Ref. EK-ES4603
| 50µl | 188,00 € | ||
| 100µl | 316,00 € |
Información del producto
- CAPN10; KIAA1845; Calpain-10; Calcium-activated neutral proteinase 10; CANP 10
Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq,
Propiedades químicas
Consulta técnica sobre: EK-ES4603 Calpain 10 rabbit pAb
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