Myosin IXb rabbit pAb

Ref. EK-ES6320

Información del producto

• Nombre: Myosin IXb rabbit pAb
• Sinónimos: MYO9B; MYR5; Unconventional myosin-IXb; Unconventional myosin-9b

Descripción

This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],

• Marca: ELK Biotechnology