Bcl-7a rabbit pAb

Ref. EK-ES7053

Información del producto

• Nombre: Bcl-7a rabbit pAb
• Sinónimos: BCL7A; B-cell CLL/lymphoma 7 protein family member A

Descripción

This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

• Marca: ELK Biotechnology