WASP (phospho Tyr290) rabbit pAb
Ref. EK-ES7513
Información del producto
Nombre:WASP (phospho Tyr290) rabbit pAb
Sinónimos:
- WAS; IMD2; Wiskott-Aldrich syndrome protein; WASp
Marca:ELK Biotechnology
Descripción:The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A t
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Consulta técnica sobre: WASP (phospho Tyr290) rabbit pAb
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