HDAC3 (phospho Ser424) rabbit pAb

Ref. EK-ES7887

Información del producto

• Nombre: HDAC3 (phospho Ser424) rabbit pAb
• Sinónimos: HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45

Descripción

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008],

• Marca: ELK Biotechnology