Capecitabine

CAS: 154361-50-9

Ref. TM-T1408

Información del producto

• Nombre: Capecitabine
• Sinónimos: Xeloda, Capecitibine, Capiibine, RO 09-1978, 1-(5-deoxypentofuranosyl)-5-fluoro-4-{[(pentyloxy)carbonyl]amino}pyrimidin-2(1H)-one, 5-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine, 5′-Deoxy-5-fluoro-N⁴-(pentyloxycarbonyl)cytidine, Capacetrine, Capecitabine Accord, Capecitabine Medac, Capecitabine SUN, Capecitabine Teva, Capecitibine, Capecytabine, Capiibine, Captabin, Carbamic acid, [1-(5-deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl]-, pentyl ester, Cytidine, 5′-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]-, Ecansya, N4-[(pentyloxy)carbonyl]-5'-deoxy-5-fluorocytidine, N⁴-Pentyloxycarbonyl-5′-deoxy-5-fluorocytidine, Pentyl [1-(3,4-dihydroxy-5-methyl-oxolan-2-yl)-5-fluoro-2-oxo-pyrimidin-4-yl]aminoformate, R-340, Ro 09-1978/000, Ro-09-1978, Xeloda, Xeltabin
• CAS: 154361-50-9

Descripción

Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 359.35
• Fórmula: C₁₅H₂₂FN₃O₆
• Pureza: 100%
• Color/Forma: Less Solid Colourless Solid