PF-5006739

CAS: 1293395-67-1

Ref. TM-T16507

Información del producto

• Nombre: PF-5006739
• CAS: 1293395-67-1

Descripción

PF-5006739 is an effective and selective inhibitor of CK1δ/ε (IC50s: 3.9 nM and 17.0 nM, respectively). PF-5006739 is a potential therapeutic agent for a range of psychiatric disorders with low nanomolar in vitro potency for CK1δ/ε and high kinome selectivity. PF-5006739 improves glucose tolerance in both diet-induced obesity (DIO) and genetic (ob/ob) mice models of obesity. PF-5006739 decreases opioid drug-seeking behavior in a rodent operant reinstatement model in animals in a dose-dependent manner.

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 419.45
• Fórmula: C₂₂H₂₂FN₇O
• Pureza: 98%