RG-12525

CAS: 120128-20-3

Ref. TM-T16739

Información del producto

• Nombre: RG-12525
• Sinónimos: NID 525, 2-[(4-{[2-(2H-tetrazol-5-ylmethyl)benzyl]oxy}phenoxy)methyl]quinoline, 2-[[4-[[2-(2H-Tetrazol-5-ylmethyl)phenyl]methoxy]phenoxy]methyl]quinoline, Nid 525, Quinoline, 2-[[4-[[2-(1H-tetrazol-5-ylmethyl)phenyl]methoxy]phenoxy]methyl]-, Quinoline, 2-[[4-[[2-(2H-tetrazol-5-ylmethyl)phenyl]methoxy]phenoxy]methyl]-, Rg-12525
• CAS: 120128-20-3

Descripción

RG-12525(NID 525) is an orally available, selective and competitive leukotriene D (LTD) antagonist that inhibits LTC4, LTD4 and LTE4-induced contraction of guinea pig thin-walled bands, with IC50 values of 2.6 nM, 2.5 nM, and 7 nM, respectively.RG-12525 inhibits CYP3A4, with a Ki value of 0.5 µM. RG-12525 is a novel and potent PPAR-γ agonist (IC50 value of about 60 nM) with species specificity for the study of asthma.

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 423.47
• Fórmula: C₂₅H₂₁N₅O₂
• Pureza: 96.77%
• Color/Forma: Solid