WR99210

CAS: 47326-86-3

Ref. TM-T17257

Información del producto

• Nombre: WR99210
• Sinónimos: WR-99210, 1,3,5-Triazine-2,4-Diamine, 1,6-Dihydro-6,6-Dimethyl-1-[3-(2,4,5-Trichlorophenoxy)Propoxy]-, Hydrochloride (1:1), 1,3,5-Triazine-2,4-diamine, 1,6-dihydro-6,6-dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-, 1,6-Dihydro-6,6-Dimethyl-1-(3-(2,4,5-Trichlorophenoxy)Propoxy)-1,3,5-Triazine-2,4-Diamine, Monohydrochloride, 1,6-Dihydro-6,6-dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,3,5-triazine-2,4-diamine, Tcmdc-137301, Wr 99210
• CAS: 47326-86-3

Descripción

WR99210 is a potent, orally available and less toxic dihydrofolate reductase (DHFR) inhibitor (IC50<0.075 nM). WR99210 has good antiparasitic activity against P. vivax and P. falciparum strains (including P. falciparum strains resistant to Pyrimethamine ) and T. gondii.

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 394.68
• Fórmula: C₁₄H₁₈Cl₃N₅O₂
• Pureza: 98%
• Color/Forma: Solid
• InChI: InChI=1S/C14H18Cl3N5O2/c1-14(2)21-12(18)20-13(19)22(14)24-5-3-4-23-11-7-9(16)8(15)6-10(11)17/h6-7H,3-5H2,1-2H3,(H4,18,19,20,21)
• Clave InChI: InChIKey=MJZJYWCQPMNPRM-UHFFFAOYSA-N
• SMILES: CC1(C)N=C(N)N=C(N)N1OCCCOc1cc(Cl)c(Cl)cc1Cl