AACOCF3

CAS: 149301-79-1

Ref. TM-T21681

Información del producto

• Nombre: AACOCF3
• Sinónimos: Arachidonyl trifluoromethyl ketone, Arachidonyltrifluoromethane, (6Z,9Z,12Z,15Z)-1,1,1-Trifluoro-6,9,12,15-heneicosatetraen-2-one, (6Z,9Z,12Z,15Z)-1,1,1-trifluorohenicosa-6,9,12,15-tetraen-2-one, 1,1,1-Trifluoro-6Z,9Z,12Z,15Z-heneicosatetraen-2-one, 6,9,12,15-Heneicosatetraen-2-one, 1,1,1-trifluoro-, (6Z,9Z,12Z,15Z)-, 6,9,12,15-Heneicosatetraen-2-one, 1,1,1-trifluoro-, (all-Z)-, AACOCF₃, An 20579, Arachidonic acid trifluoromethyl ketone, Arachidonyl trifluoromethyl ketone, Arachidonyltrifluoromethane, Atfmk, Bm 162353, L 734575, Pacocf3
• CAS: 149301-79-1

Descripción

AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid. It is a potent and selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). By blocking the production of arachidonate and 12-hydroxyeicosatetraenoic acid in calcium ionophore-challenged platelets, AACOCF3 hinders their synthesis. Moreover, AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets. Given its diverse applications, AACOCF3 holds promise for cardiovascular disease research.

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 356.47
• Fórmula: C₂₁H₃₁F₃O
• Pureza: 98%
• Color/Forma: Yellow Liquid