PX-12

CAS: 141400-58-0

Ref. TM-T2283

Información del producto

• Nombre: PX-12
• Sinónimos: IV-2, PX12, MID, Iv-2, Px-12, 2-(butan-2-yldisulfanyl)-1H-imidazole
• CAS: 141400-58-0

Descripción

PX-12 (PX12) (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor growth in animal models. Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated as a potential cancer treatment in combination with chemotherapy for patients with advanced metastatic cancer. Initial trials correlated doses of Px-12 with increased patient survival.

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 188.31
• Fórmula: C₇H₁₂N₂S₂
• Pureza: 99.6%
• Color/Forma: Solid