CHIR-99021 HCl

CAS: 1797989-42-4

Ref. TM-T2310L

Información del producto

• Nombre: CHIR-99021 HCl
• Sinónimos: CT99021 HCl, Laduviglusib HCl
• CAS: 1797989-42-4

Descripción

CHIR-99021 HCl (Laduviglusib HCl) is a highly potent and selective inhibitor of GSK-3α/β, with IC50 values of 10 nM and 6.7 nM respectively. It demonstrates remarkable selectivity for GSK-3, with over 500-fold selectivity over CDC2, ERK2, and other protein kinases. Additionally, CHIR-99021 HCl serves as a robust activator of the Wnt/β-catenin signaling pathway. Moreover, it exhibits the ability to enhance self-renewal in both mouse and human embryonic stem cells. Furthermore, CHIR-99021 HCl induces autophagy [1] [2] [3].

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 501.8
• Fórmula: C₂₂H₁₉Cl₃N₈
• Pureza: 98.07%
• Color/Forma: Solid