Bromfenac sodium hydrate

CAS: 120638-55-3

Ref. TM-T2403

Información del producto

• Nombre: Bromfenac sodium hydrate
• Sinónimos: Bromfenac sodium, Bromfenac monosodium salt sesquihydrate, 2-Amino-3-(4-bromobenzoyl)phenylacetic acid sodium salt, Benzeneacetic acid, 2-amino-3-(4-bromobenzoyl)-, monosodium salt, hydrate (2:3), Benzeneacetic acid, 2-amino-3-(4-bromobenzoyl)-, sodium salt, hydrate (2:2:3), Sodium [2-amino-3-(4-bromobenzoyl)phenyl]acetate, Sodium {2-Amino-3-[(4-Bromophenyl)Carbonyl]Phenyl}Acetate Hydrate, Yellox, [2-Amino-3-(4-Bromobenzoyl)Phenyl]Acetic Acid
• CAS: 120638-55-3

Descripción

Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is the sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory activities. Upon ophthalmic administration, bromfenac binds to and inhibits the activity of cyclooxygenase II (COX II), an enzyme which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins (PG). By inhibiting PG formation, bromfenac is able to inhibit PG-induced inflammation, thereby preventing vasodilation, leukocytosis, disruption of the blood-aqueous humor barrier, an increase in vascular permeability and an increase in intraocular pressure (IOP).

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 383.17
• Fórmula: C₁₅H₁₂BrNO₃H₂O·Na
• Pureza: 99.65%
• Color/Forma: Solid