Mabuterol free base

CAS: 56341-08-3

Ref. TM-T27970

Información del producto

• Nombre: Mabuterol free base
• Sinónimos: Mabuterol, PB 868Cl, 1-[4-Amino-3-Chloro-5-(Trifluoromethyl)Phenyl]-2-(Tert-Butylamino)Ethanol, 4-Amino-3-chloro-α-[[(1,1-dimethylethyl)amino]methyl]-5-(trifluoromethyl)benzenemethanol, 4-Amino-alpha-((tert-butylamino)methyl)-3-chloro-5-(trifluoromethyl)benzyl alcohol, Ambuterol, Benzenemethanol, 4-amino-3-chloro-alpha-(((1,1-dimethylethyl)amino)methyl)-5-(trifluoromethyl)-, Benzenemethanol, 4-amino-3-chloro-α-[[(1,1-dimethylethyl)amino]methyl]-5-(trifluoromethyl)-, Ccris 5288, Mabuterol [INN], Mabuterolum, Mabuterolum [INN-Latin], PB 868Cl, Unii-R4K19W6S7Q
• CAS: 56341-08-3

Descripción

Mabuterol is a selective agonist of β2 adrenoreceptor with no beta 1-stimulation. Mabuterol inhibited the positive inotropic effect of isoprenaline at 10(-7) g/ml and decreased the maximum driving frequency at 3 X 10(-6) g/ml. Mabuterol was 3 times more potent in relaxing the isolated rat uterus, but 700 times less potent than isoprenaline in relaxing the rabbit jejunum. Mabuterol (p.o.) depressed the intestinal propulsion and was equipotent to isoprenaline and 2.5 times less potent than salbutamol.

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 310.74
• Fórmula: C₁₃H₁₈ClF₃N₂O
• Pureza: 98%
• Color/Forma: Solid