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Setipiprant
CAS: 866460-33-5
Ref. TM-T3520
10mg | 46,00 € | ||
25mg | 78,00 € | ||
50mg | 114,00 € | ||
100mg | 176,00 € | ||
200mg | 260,00 € | ||
1ml*10 (DMSO) | 35,00 € |
Información del producto
- KYTH-105, ACT-129968
Setipiprant (ACT-129968) is an orally available, selective CRTH2 antagonist (IC50: 6.0 nM). CRTH2 is a G protein-coupled receptor for prostaglandin (PGD2). PGD2 is produced by the mast cells and is a key mediator in various inflammatory diseases, including allergy and asthma. Binding of PGD2 to CRTH2, which are expressed on the surface of blood-borne cells, induces chemotaxis of Th2 cells, basophils, and eosinophils, and stimulates cytokine release from these cells.
Propiedades químicas
Consulta técnica sobre: TM-T3520 Setipiprant
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