Mivebresib
CAS: 1445993-26-9
Ref. TM-T3712
1mg | 58,00 € | ||
2mg | 81,00 € | ||
5mg | 95,00 € | ||
10mg | 157,00 € | ||
25mg | 251,00 € | ||
50mg | 453,00 € | ||
100mg | 646,00 € | ||
1ml*10 (DMSO) | 97,00 € |
Información del producto
- ABBV-075
Mivebresib (ABBV-075), also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-containing protein) with potential antineoplastic activity. Upon administration, the bromodomain inhibitor ABBV-075 binds to the acetyl-lysine binding site in the BRD of certain BRD-containing protein(s), thereby preventing the interaction between those proteins and acetylated histones. This disrupts chromatin remodeling, prevents the expression of certain growth-promoting genes, and leads to an inhibition of cell growth in susceptible tumors. Also a potent inhibitor of MYC and the TMPRSS2-ETS fusion proteins.
Propiedades químicas
Consulta técnica sobre: TM-T3712 Mivebresib
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