RORγt Inverse agonist 10

CAS: 2413986-35-1

Ref. TM-T40043

Información del producto

• Nombre: RORγt Inverse agonist 10
• Marca: Targetmol
• Descripción: RORγt Inverse agonist 10 is a highly potent, orally bioavailable compound that acts as an antagonist for the retinoic acid receptor-related orphan nuclear receptor gamma t (RORγt). With an IC50 of 51 nM, it effectively inhibits RORγt activity, a key transcription factor regulating genes linked to psoriasis pathogenesis, including [IL-17A], [IL-22], and [IL-23R].

Propiedades químicas

• Peso molecular: 572.512
• Fórmula: C₂₅H₂₆F₆N₆O₃
• Color/Forma: Solid