CLOZAPINE N-OXIDE
CAS: 34233-69-7
Ref. TM-T4494
2mg | 40,00 € | ||
5mg | 54,00 € | ||
10mg | 87,00 € | ||
25mg | 126,00 € | ||
50mg | 179,00 € | ||
100mg | 264,00 € | ||
1ml*10 (DMSO) | 54,00 € |
Información del producto
- CLOZAPINE NOXIDE
- 5H-Dibenzo(b,e)(1,4)diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-, N-oxide
- 5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-4-oxido-1-piperazinyl)-
- 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine N-oxide
- 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine
- 8-chloro-11-(4-methylpiperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepin-10-ol
- Vufb-12426
Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration [1]. It is produced by the action of cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4, whose activities, in turn, can be affected by drugs and disease [2]. Clozapine N-oxide is normally biologically inactive. However, it can be used in designer receptor exclusively activated by designer drugs, also known as DREADDs, technology to modulate synthetic receptors in vivo [3].
Propiedades químicas
Consulta técnica sobre: TM-T4494 CLOZAPINE N-OXIDE
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