Fosbretabulin Disodium

CAS: 168555-66-6

Ref. TM-T6272

Información del producto

• Nombre: Fosbretabulin Disodium
• Sinónimos: Combretastatin A4 Phosphate, CA 4DP, CA 4P, Combretastatin A4 disodium phosphate, Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium, 2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol dihydrogen phosphate disodium salt, Ca 4Dp, Ca 4P, Ca4P, CombretastatinA4disodiumphosphate(CA4P), Fosbretabulin disodium, Fosbretabulin disodium salt, Ombretastatin A-4 Phosphate, Disodium Salt, Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1-(dihydrogen phosphate), sodium salt (1:2), Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, dihydrogen phosphate, disodium salt, Phenol, 2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]-, dihydrogen phosphate, disodium salt, (Z)-, Sml1131, disodium 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl phosphate
• CAS: 168555-66-6

Descripción

Fosbretabulin Disodium (CA 4P), a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM). Fosbretabulin Disodium(Combretastatin A4 disodium phosphate) inhibits the polymerization of tubulin (IC50: 2.4 μM), and also disrupts tumor vasculature.

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 440.29
• Fórmula: C₁₈H₁₉O₈P·2Na
• Pureza: 99.96%
• Color/Forma: White Solid