Dofetilide

CAS: 115256-11-6

Ref. TM-T6476

Información del producto

• Nombre: Dofetilide
• Sinónimos: UK 68789, UK-68798, Tikosyn, Methanesulfonamide, N-[4-[2-[methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]-, N-(4-{2-[Methyl(2-{4-[(methylsulfonyl)amino]phenoxy}ethyl)amino]ethyl}phenyl)methanesulfonamide, N-(4-{2-[Methyl(2-{4-[(methylsulfonyl)amino]phenoxy}ethyl)amino]ethyl}phenyl)methansulfonamid, N-[4-[2-[Methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]methanesulfon Amide, Tikosyn, Uk 68798
• CAS: 115256-11-6

Descripción

Dofetilide (UK 68789) is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ikr. This antiarrhythmic agent prolongs cardiac action potential duration and effective refractory period due to delayed repolarization without affecting conduction velocity. This results in a normal sinus rhythm. Dofetilide is used in the treatment of atrial fibrillation and flutter.

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 441.56
• Fórmula: C₁₉H₂₇N₃O₅S₂
• Pureza: 99.06%
• Color/Forma: Off-White Or Yellowish Crystalline Powder