PF-6689840
CAS:
Ref. TM-T67693
Información del producto
Nombre:PF-6689840
Marca:Targetmol
Descripción:PF-6689840 is a potent and selective Type II PTK6/Brk inhibitor with IC50 of 54 nM in biochemical assays; inhibits PTK6 phosphorylation at Y342 in engineered HET293T cells overexpressing PTK6 WT with IC50 of 0.25 uM; demonstrates superior kinase selectivity compared to the Type I inhibitors; inhibits tumor cell growth, which is independent of PTK6 expression levels in cells.
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Propiedades químicas
Peso molecular:521.46
Fórmula:C24H23F4N5O4
Color/Forma:Soild