Bisdemethoxycurcumin

CAS: 24939-16-0

Ref. TM-TL0007

Información del producto

• Nombre: Bisdemethoxycurcumin
• Sinónimos: Curcumin III, Didemethoxycurcumin, (1E,6E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione, (1E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione, 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, 1,6-Heptadiene-3,5-dione, 1,7-bis(p-hydroxyphenyl)-, 1,7-Bis(4-Hydroxyphenyl)Hepta-1,6-Diene-3,5-Dione, 1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione, Bis(4-hydroxycinnamoyl)methane, Bisdemethoxycucurmin, p,p′-Dihydroxydicinnamoylmethane
• CAS: 24939-16-0

Descripción

Bisdemethoxycurcumin (Curcumin III) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by macrophages (optimal stimulation at 100 nM BDMC) [1]. More stable than curcumin in physiological media, BDMC suppresses proliferation of cancer cells [2]. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits LPS induction of iNOS expression [3].

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 308.33
• Fórmula: C₁₉H₁₆O₄
• Pureza: 99.34%
• Color/Forma: Solid