Siglec-2/CD22 Protein, Human, Recombinant (His & Avi), Biotinylated
Ref. TM-TMPJ-00392
20µg | 357,00 € | ||
100µg | 948,00 € |
Información del producto
- T-cell surface antigen Leu-14, CD22 molecule, CD22, SIGLEC2FLJ22814, sialic acid binding Ig-like lectin 2, CD22 antigenMGC130020, B-cell receptor CD22, BL-CAM, Siglec-2, B-lymphocyte cell adhesion molecule
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Human Siglec-2, also known as B-cell antigen CD22 or B-lymphocyte cell adhesion molecule (BL-CAM), is a B-cell restricted glycoprotein that is expressed in the cytoplasm of progenitor B and pre-B cells and on the surface of mature B cells. Two distinct human Siglec-2/CD22 cDNAs that arise from differential RNA processing of the same gene have been isolated. Siglec-2/CD22 is an adhesion molecule that preferentially binds alpha 2,6- linked sialic acid on the same (cis) or adjacent (trans) cells. Interaction of CD22 with trans ligands on opposing cells was found to be favored over the binding of ligands in cis.
Propiedades químicas
Consulta técnica sobre: TM-TMPJ-00392 Siglec-2/CD22 Protein, Human, Recombinant (His & Avi), Biotinylated
Si desea solicitar un presupuesto o realizar un pedido, por favor añada los productos deseados a su carrito y solicite un presupuesto o pedido desde el carrito. Es más rápido, más barato, y podrá beneficiarse de los descuentos y las ventajas disponibles.