OGG1 Protein, Human, Recombinant
Ref. TM-TMPJ-00457
1mg | 2.602,00 € | ||
10µg | 135,00 € | ||
50µg | 392,00 € | ||
500µg | 1.811,00 € |
Información del producto
- OGH1, N-Glycosylase/DNA Lyase, DNA-(Apurinic or Apyrimidinic Site) Lyase, AP Lyase, MMH, 8-Oxoguanine DNA Glycosylase, MUTM, OGG1
Human N-Glycosylase/DNA Lyase(OOG1) is a DNA repair enzyme, which belongs to the type-1 OGG1 family. OOG1 incises DNA at 8-oxoG residues, and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damage DNA. It has a β-lyase activity that nicks DNA 3’ to the lesion. OOG1 together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells. The OGG1 gene mutations may be caused Renal cell carcinoma.
Propiedades químicas
Consulta técnica sobre: TM-TMPJ-00457 OGG1 Protein, Human, Recombinant
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