SUMO2 Protein, Human, Recombinant (His)
Ref. TM-TMPJ-00486
1mg | 347,00 € | ||
10µg | 12,00 € | ||
50µg | 44,00 € | ||
500µg | 243,00 € |
Información del producto
- HSMT3, Ubiquitin-Like Protein SMT3A, SUMO-3, SMT3A, Sentrin-2, SMT3H2, SUMO-2, Small Ubiquitin-Related Modifier 2, SUMO2, SMT3 homolog 2
Small Ubiquitin-Related Modifier 2 (SUMO2) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. SUMO2 can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptidebond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.
Propiedades químicas
Consulta técnica sobre: TM-TMPJ-00486 SUMO2 Protein, Human, Recombinant (His)
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