DNA PolymeraseBeta Protein, Human, Recombinant (His)
Ref. TM-TMPJ-00792
1mg | 2.521,00 € | ||
10µg | 124,00 € | ||
50µg | 361,00 € | ||
500µg | 1.755,00 € |
Información del producto
- DNA Polymeraseβ, POLB, DNA Polymerase Beta, DNA Polymerase β
Human DNA polymerase β is constitutively expressed in cells. It fills in gaps in DNA that are formed following base excision repair. Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. It conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. The activity cannot be affected by Aphidicolin, which is an inhibitor of DNA polymerase β.
Propiedades químicas
Consulta técnica sobre: TM-TMPJ-00792 DNA PolymeraseBeta Protein, Human, Recombinant (His)
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