NFKB1 Protein, Human, Recombinant (His)

Ref. TM-TMPJ-00887

Información del producto

• Nombre: NFKB1 Protein, Human, Recombinant (His)
• Sinónimos: Nuclear factor of κ light polypeptide gene enhancer in B-cells 1, DNA-binding factor KBF1, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, EBP-1

Descripción

The 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 45-55 KDa (reducing condition)
• Color/Forma: Solid