CDKN1B Protein, Human, Recombinant (His)
Ref. TM-TMPJ-00972
1mg | 2.521,00 € | ||
10µg | 170,00 € | ||
50µg | 504,00 € | ||
500µg | 1.755,00 € |
Información del producto
- KIP1, CDKN1B, Cyclin-Dependent Kinase Inhibitor p27, Cyclin-Dependent Kinase Inhibitor 1B, p27Kip1
Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B) is a Kinesin-related motor protein necessary for mitotic spindle assembly and chromosome segregation. CDKN1B is expressed in all tissues with highest levels observed in skeletal muscle. CDKN1B is a potent inhibitor of Cyclin E- and Cyclin A-CDK2 complexes. CDKN1B forms a complex with Cyclin Type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. In addition, CDKN1B acts as an inhibitor or an activator of Cyclin Type D-CDK4 complexes depending on its phosphorylation state and stoichometry.
Propiedades químicas
Consulta técnica sobre: TM-TMPJ-00972 CDKN1B Protein, Human, Recombinant (His)
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