FGFR3 β (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

Ref. TM-TMPK-00387

Información del producto

• Nombre: FGFR3 β (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
• Sinónimos: HSFGFR3EX, FGF R3, EC 2.7.10, CD333, FGFR3 β (IIIc), CEK2, FGFR3, JTK4, CEK, ACH

Descripción

Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts..

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 30.1 kDa (predicted). Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
• Color/Forma: Solid