IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated

Ref. TM-TMPK-00456

Información del producto

• Nombre: IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated
• Sinónimos: CD221, MGC142172, IGFIR, IGFR, MGC18216, JTK13, IGF-I R, IGF-1R, IGF-I receptor, MGC142170, IGF1R

Descripción

The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target. IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 105.8 kDa (alpha subunit) and 23 kDa (beta subunit) and the accession number is P08069.

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa (alpha subunit) and 52-55 kDa (beta subunit) based on Tris-Bis PAGE result.
• Color/Forma: Solid