Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (aa 291-696, His)
Ref. TM-TMPY-05331
100µg | 686,00 € |
Información del producto
Envelope of Zika virus is responsible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent with those reported for dengue, YFYF and Japanese encephalitis. The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross-reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross-reactivity with dengue and YF.Domain III of the Zika envelope protein, likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76% of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus.
Propiedades químicas
Consulta técnica sobre: TM-TMPY-05331 Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (aa 291-696, His)
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