Ingenol mebutate

CAS: 75567-37-2

Ref. TM-TN1047

Información del producto

• Nombre: Ingenol mebutate
• Sinónimos: Ingenol 3-Angelate, PEP005, 1H-2,8a-Methanocyclopenta[a]cyclopropa[e]cyclodecene, 2-butenoic acid deriv., 2-Butenoic acid, 2-methyl-, (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester, (2Z)-, 2-Butenoic acid, 2-methyl-, 1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester, [1aR-[1aα,2β,5β,5aβ,6β(Z),8aα,9α,10aα]]-, 3-Angeloylingenol, Aids-416619, Aids416619, Euphorbia factor An₁, Euphorbia factor H₁, I3A, Ingenol 3-angelate, Ingenol 3-mebutate, Pep 005, Picato
• CAS: 75567-37-2

Descripción

Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory and antitumor activity.

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 430.53
• Fórmula: C₂₅H₃₄O₆
• Pureza: 99.04%
• Color/Forma: Solid