Abiraterone

CAS: 154229-19-3

Ref. TR-A108490

Información del producto

• Nombre: Abiraterone
• Sinónimos: CB 7598, (3beta)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol, 17-(3-Pyridinyl)-androsta-5,16-dien-3beta-ol, (3Beta)-17-(Pyridin-3-Yl)Androsta-5,16-Dien-3-Ol, (3b)-17-(3-pyridinyl)-Androsta-5,16-dien-3-ol, 17-(3-Pyridinyl)-androsta-5,16-dien-3β-ol, 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol, Androsta-5,16-dien-3-ol, 17-(3-pyridinyl)-, (3β)-, Cb 7598
• CAS: 154229-19-3

Descripción

Applications Abiraterone is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389 (2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005);

• Marca: TRC

Propiedades químicas

• Peso molecular: 349.51
• Fórmula: C₂₄H₃₁NO
• Color/Forma: White
• InChI: InChI=1S/C24H31NO/c1-23-11-9-18(26)14-17(23)5-6-19-21-8-7-20(16-4-3-13-25-15-16)24(21,2)12-10-22(19)23/h3-5,7,13,15,18-19,21-22,26H,6,8-12,14H2,1-2H3/t18-,19-,21-,22-,23-,24+/m0/s1
• Clave InChI: InChIKey=GZOSMCIZMLWJML-VJLLXTKPSA-N
• SMILES: C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]43C)[C@@H]1CC=C2c1cccnc1