Acarviosin

CAS: 80943-41-5

Ref. TR-A123550

Información del producto

• Nombre: Acarviosin
• Sinónimos: Acarviosine, (S)-Acarviosin, [1S-(1a,4a,5ß,6a)]-4,6-Dideoxy-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-a-D-glucopyranoside Methyl Ester, 4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-a-D-glucopyranoside Methyl Ester, Methyl 4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-<span class="text-smallcaps">D</span>-glucopyranoside, a-D-Glucopyranoside, methyl4,6-dideoxy-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-,[1S-(1a,4a,5b,6a)]-, α-<span class="text-smallcaps">D</span>-Glucopyranoside, methyl 4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-, α-<span class="text-smallcaps">D</span>-Glucopyranoside, methyl 4,6-dideoxy-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-, [1S-(1α,4α,5β,6α)]-

Descripción

Stability Hygroscopic
Applications Acarviosin is a part of the potent α-amylase inhibitor, Acarbose (A123500), an anti-diabetic drug used to treat type 2 diabetes mellitus (1,2,3).
References (1) Shibata, Y., et al.: Carbohydrate. Res., 228, 377 (1992) (2) Raimbaud, E., et al.: Carbohydrate. Res., 227, 351 (1992) (3) Geng, P., et al.: Carbohydr Res. 343, 882 (2008)https://www.ncbi.nlm.nih.gov/pubmed/18294624PMID: 18294624

• Marca: TRC

Propiedades químicas

• Peso molecular: 335.35
• Fórmula: C₁₄H₂₅NO₈
• Color/Forma: White
• InChI: InChI=1S/C14H25NO8/c1-5-8(11(19)13(21)14(22-2)23-5)15-7-3-6(4-16)9(17)12(20)10(7)18/h3,5,7-21H,4H2,1-2H3/t5-,7+,8-,9-,10+,11+,12+,13-,14+/m1/s1
• Clave InChI: InChIKey=KFHKERRGDZTZQJ-LXGKPMTPSA-N
• SMILES: COC1O[C@H](C)[C@@H](N[C@H]2C=C(CO)[C@H](O)[C@H](O)[C@H]2O)C(O)C1O