AMD 3465

CAS: 185991-07-5

Ref. TR-A576350

Información del producto

• Nombre: AMD 3465
• Sinónimos: N-[[4-(1,4,8,11-tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine Hydrobromide, GENZ 644494, 2-Pyridinemethanamine, N-((3-(1,4,8,11-tetraazacyclotetradec-1-ylmethyl)phenyl)methyl)-, 2-Pyridinemethanamine, N-[[4-(1,4,8,11-tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-, hexahydrobromide, 2-Pyridinemethanamine, N-[[4-(1,4,8,11-tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-, hydrobromide (1:6), Amd 3465, Genz 644494
• CAS: 185991-07-5

Descripción

Applications AMD 3465 is a CXCR4 antagonist and in combination with monoclonal antibody, was shown to be potentially effective in reducing tumor growth and increasing survival in patient with B cell lymphoma
References Burger, J.A., et al.: Leuke. Lympho.,53. 3 (2012); Lam, A.R., et al.: J. Chem. Info. Model., 51, 139 (2011); De Clercq. E., et al.: Pharmacol. Therap., 128. 509 (2010);

• Marca: TRC

Propiedades químicas

• Peso molecular: 896.07
• Fórmula: C₂₄H₄₄Br₆N₆
• Color/Forma: Pale Yellow Solid
• InChI: InChI=1S/C24H38N6.6BrH/c1-2-13-29-24(5-1)20-28-19-22-6-8-23(9-7-22)21-30-17-4-12-26-15-14-25-10-3-11-27-16-18-30;;;;;;/h1-2,5-9,13,25-28H,3-4,10-12,14-21H2;6*1H