4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid Methyl Ester

CAS: 155405-80-4

Ref. TR-A604950

Información del producto

• Nombre: 4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid Methyl Ester
• Sinónimos: Benzoic acid, 4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-, methyl ester, Benzoic acid, 4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-, methyl ester (9CI), 1H-Pyrrolo[2,3-d]pyrimidine, benzoic acid deriv., 1H-Pyrrolo[2,3-d]pyrimidine, benzoic acid deriv., Methyl 4-[2-(2-Amino-4-Oxo-1,7-Dihydropyrrolo[4,5-E]Pyrimidin-5-Yl)Ethyl]Benzoate, Methyl 4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate, Methyl 4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate, Methyl 4-[2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate, benzoic acid, 4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-, methyl ester, benzoic acid, 4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-, methyl ester

Descripción

Applications An intermediate in the preparation of Pemetrexed Disodium (P219500) and its derivatives as anticancer agents.
References Min, T. et al.: Med. Chem. Res., 18, 495 (2009); Ma, Y. et al.: Zhong. Xin. Zaz., 16, 134 (2007);

• Marca: TRC

Propiedades químicas

• Peso molecular: 312.32
• Fórmula: C₁₆H₁₆N₄O₃
• Color/Forma: Neat
• InChI: InChI=1S/C16H16N4O3/c1-23-15(22)10-5-2-9(3-6-10)4-7-11-8-18-13-12(11)14(21)20-16(17)19-13/h2-3,5-6,8H,4,7H2,1H3,(H4,17,18,19,20,21)
• Clave InChI: InChIKey=GDEKSBCRJKAARB-UHFFFAOYSA-N
• SMILES: COC(=O)c1ccc(CCc2c[nH]c3[nH]c(=N)[nH]c(=O)c23)cc1