(5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone

CAS: 141644-91-9

Ref. TR-A617575

Información del producto

• Nombre: (5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone
• Sinónimos: Methanone, (5-amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]-, 5-Amino-2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]benzofuran, Methanone, (5-Amino-2-Butyl-3-Benzofuranyl)[4-[3-(Dibutylamino)Propoxy]Phenyl]-
• CAS: 141644-91-9

Descripción

Applications (5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone is an intermediate used in the synthesis of dronedarone hydrochloride (I), a class III antiarrhythmia drug for the prevention of cardiac arrhythmias such as atrial fibrillation.
References Mali, A. C., et al.: Org. Proc. Res. Dev., 17, 863 (2013)

• Marca: TRC

Propiedades químicas

• Peso molecular: 478.67
• Fórmula: C₃₀H₄₂N₂O₃
• Color/Forma: Neat
• InChI: InChI=1S/C30H42N2O3/c1-4-7-11-28-29(26-22-24(31)14-17-27(26)35-28)30(33)23-12-15-25(16-13-23)34-21-10-20-32(18-8-5-2)19-9-6-3/h12-17,22H,4-11,18-21,31H2,1-3H3
• Clave InChI: InChIKey=SPIIBUQYWNFELT-UHFFFAOYSA-N
• SMILES: CCCCc1oc2ccc(N)cc2c1C(=O)c1ccc(OCCCN(CCCC)CCCC)cc1