4-[4-(4-Aminophenyl)-1-piperazinyl]phendiamineol

CAS: 74853-08-0

Ref. TR-A626090

Información del producto

• Nombre: 4-[4-(4-Aminophenyl)-1-piperazinyl]phendiamineol
• Sinónimos: Posaconazole Impurity, 4-[4-(4-aminophenyl)-1-piperazinyl]phenol, 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine, 4-(4-(4-Aminophenyl)Piperazin-1Yl)Phenol, 4-(4-Aminophenyl)-1-(4-hydroxyphenyl) piperazine, 4-[4-(4-Aminophenyl)-1-piperazinyl]phenol, 4-[4-(4-Aminophenyl)piperazin-1-yl]benzolol, 4-[4-(4-Aminophenyl)piperazin-1-yl]phenol, Phenol, 4-[4-(4-Aminophenyl)-1-Piperazinyl]-, Posaconazole Intermediate, 1-(4-Nitrophenyl)-4-(4-hydroxyphenyl)piperazine

Descripción

Applications 4-[4-(4-Aminophenyl)-1-piperazinyl]phendiamineol is an intermediate of Posaconazole (P689600), which is orally active antifungal triazole.
References Cacciapuoti, A., et al.: Antimicrob. Agents Chemother., 44, 2017 (2000); Herbrecht, R., et al.: Int. J. Clin. Pract., 58, 612 (2004); Panackal, A., et al.: J. Clin. Microbiol., 44, 1740 (2006); Yan, X., et al.: Guangzhou Huagong, 41, 107 (2013);

• Marca: TRC

Propiedades químicas

• Peso molecular: 269.34
• Fórmula: C₁₆H₁₉N₃O
• Color/Forma: Neat
• InChI: InChI=1S/C16H19N3O/c17-13-1-3-14(4-2-13)18-9-11-19(12-10-18)15-5-7-16(20)8-6-15/h1-8,20H,9-12,17H2
• Clave InChI: InChIKey=WZIJMPVPOMTRNM-UHFFFAOYSA-N
• SMILES: Nc1ccc(N2CCN(c3ccc(O)cc3)CC2)cc1