Amopyroquine

CAS: 550-81-2

Ref. TR-A634215

Información del producto

• Nombre: Amopyroquine
• Sinónimos: o-Cresol, 4-[(7-chloro-4-quinolyl)amino]-a-1-pyrrolidinyl- (6CI,7CI,8CI), 4-[(7-Chloro-4-quinolyl)amino]-a-1-pyrrolidinyl-o-cresol, Amopyroquin, PAM-780, Propoquin, Phenol, 4-[(7-chloro-4-quinolinyl)amino]-2-(1-pyrrolidinylmethyl), 4-(7-Chloro-4-Quinolylamino)-Alpha-Pyrrolidin-1-Yl-O-Cresol, 4-(7-Chloroquinolin-1-ylamino)-2-(1-pyrrolidinylmethyl)phenol, 4-[(7-Chloro-4-quinolinyl)amino]-2-(1-pyrrolidinylmethyl)phenol, 4-[(7-Chloro-4-quinolyl)amino]-α-1-pyrrolidinyl-o-cresol, 4-[(7-Chloroquinolin-4-Yl)Amino]-2-(Pyrrolidin-1-Ylmethyl)Phenol, Pam-780, Phenol, 4-[(7-chloro-4-quinolinyl)amino]-2-(1-pyrrolidinylmethyl)-, o-Cresol, 4-[(7-chloro-4-quinolyl)amino]-α-1-pyrrolidinyl-

Descripción

Applications Antimalarial agent. The compound showed antimalarial activity similar to that of Chloroquine.
References Desjardins, R., et al.: Antimicrob. Agents Chemother., 16, 710 (1979), McKie, J., et al.: J. Med. Chem., 41, 1367 (1998), Gozalbes, R., et al.: J. Pharm. Pharmacol., 52, 111 (1999), Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 1293 (2005),

• Marca: TRC

Propiedades químicas

• Peso molecular: 353.85
• Fórmula: C₂₀H₂₀ClN₃O
• Color/Forma: Neat
• InChI: InChI=1S/C20H20ClN3O/c21-15-3-5-17-18(7-8-22-19(17)12-15)23-16-4-6-20(25)14(11-16)13-24-9-1-2-10-24/h3-8,11-12,25H,1-2,9-10,13H2,(H,22,23)
• Clave InChI: InChIKey=YNWCUCSDUMVJKR-UHFFFAOYSA-N
• SMILES: Oc1ccc(Nc2ccnc3cc(Cl)ccc23)cc1CN1CCCC1