Anagrelide Hydrochloride

CAS: 58579-51-4

Ref. TR-A637300

Información del producto

• Nombre: Anagrelide Hydrochloride
• Sinónimos: 6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one, Imidazo[2,1-b]quinazolin-2(3H)-one, 6,7-dichloro-1,5-dihydro-, monohydrochloride (9CI), 6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one Hydrochloride, Agrelin, Agrylin, BL 4162A, BMY 26538-01, 6,7-Dichloro-1,5-dihydroimidazo(2,1-b)-quinazolin-2(3H)-one monohydrochloride, 6,7-dichloro-5,10-dihydroimidazo[2,1-b]quinazolin-2(3H)-one hydrochloride (1:1), Anagrelide hcl, Bl 4162A, Bmy 26538-01, Imidazo[2,1-b]quinazolin-2(3H)-one, 6,7-dichloro-1,5-dihydro-, hydrochloride (1:1), Imidazo[2,1-b]quinazolin-2(3H)-one, 6,7-dichloro-1,5-dihydro-, monohydrochloride

Descripción

Applications Anagrelide Hydrochloride is a phosphodiesterase inhibitor with antiplatelet activity. Used as an antithrombocythemic. Potent PDE3 inhibitor.
References Fleming, J.S., et al.: Thromb. Res., 15, 373 (1979), Seiler, S., et al.: J. Pharmacol. Exp. Ther., 243, 767 (1984), Silverstein, M. N., et al.: N. Engl. J. Med., 318, 1292 (1988), Spencer, C.M., et al.: Drugs, 47, 809 (1994),

• Marca: TRC

Propiedades químicas

• Peso molecular: 292.55
• Fórmula: C₁₀H₇Cl₂N₃O·ClH
• Color/Forma: White
• InChI: InChI=1S/C10H7Cl2N3O.ClH/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7, 1H, /h1-2H,3-4H2,(H,13,14,16)
• Clave InChI: InChIKey=TVWRQCIPWUCNMI-UHFFFAOYSA-N
• SMILES: Cl.O=C1CN2Cc3c(ccc(Cl)c3Cl)N=C2N1