6-Anilino-5,8-quinolinedione

CAS: 91300-60-6

Ref. TR-A664500

Información del producto

• Nombre: 6-Anilino-5,8-quinolinedione
• Sinónimos: 6-anilinoquinoline-5,8-dione, 5,8-Dihydro-5,8-dioxo-6-(phenylamino)quinoline, 5,8-Quinolinedione, 6-(phenylamino)-, 6-(Phenylamino)-5,8-quinolinedione, 6-Anilinoquinoline-5,8-quinone, Comr 2029, Ly 83583, Ly83583

Descripción

Applications Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2µM) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release.
References Macleod, K.M., et al.: Mol. Pharmacol., 32, 59 (1987), Mulsch, A. J.: J. Pharmacol. Exp. Ther., 247, 283 (1988), Mulsch, A., et al.: Naunyn-Schmiedeberg's Arch. Pharmacol., 340, 119 (1989), Light, D.B., et al.: Science, 243, 383 (1989), Beasley, D., et al.: J. Clin. Invest., 87, 602 (1991)

• Marca: TRC

Propiedades químicas

• Peso molecular: 250.25
• Fórmula: C₁₅H₁₀N₂O₂
• Color/Forma: Neat
• InChI: InChI=1S/C15H10N2O2/c18-13-9-12(17-10-5-2-1-3-6-10)15(19)11-7-4-8-16-14(11)13/h1-9,17H
• Clave InChI: InChIKey=GXIJYWUWLNHKNW-UHFFFAOYSA-N
• SMILES: O=C1C(Nc2ccccc2)=CC(=O)c2ncccc21