Apoptozole

CAS: 1054543-47-3

Ref. TR-A729045

Información del producto

• Nombre: Apoptozole
• Sinónimos: 4-[[2-[3,5-Bis(trifluoromethyl)phenyl]-4,5-bis(4-methoxyphenyl)-1H-imidazol-1-yl]methyl]-benzamide
• CAS: 1054543-47-3

Descripción

Applications Apoptozoleis an inhibitor of heat shock protein 70 (Hsp70) and acts by blocking its ATPase activity. Induces apoptosis in cancer cells.
References Ko, S. et al.: Chem. Biol., 22, 391 (2015); Ljung, B. et al.: J. Cardiovasc. Pharmacol., 15, S11 (1990);

• Marca: TRC

Propiedades químicas

• Peso molecular: 625.56
• Fórmula: C₃₃H₂₅F₆N₃O₃
• Color/Forma: White Solid
• InChI: InChI=1S/C33H25F6N3O3/c1-44-26-11-7-20(8-12-26)28-29(21-9-13-27(45-2)14-10-21)42(18-19-3-5-22(6-4-19)30(40)43)31(41-28)23-15-24(32(34,35)36)17-25(16-23)33(37,38)39/h3-17H,18H2,1-2H3,(H2,40,43)
• Clave InChI: InChIKey=ZIMMTPFXOMAJTQ-UHFFFAOYSA-N
• SMILES: COc1ccc(-c2nc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)n(Cc3ccc(C(N)=O)cc3)c2-c2ccc(OC)cc2)cc1