Benznidazole

CAS: 22994-85-0

Ref. TR-B197925

Información del producto

• Nombre: Benznidazole
• Sinónimos: N-benzyl-2-(2-nitroimidazol-1-yl)acetamide, 1H-Imidazole-1-acetamide, 2-nitro-N-(phenylmethyl)-, 2-Nitro-N-(phenylmethyl)-1H-imidazole-1-acetamide, Benznidazol, Benzonidazol, Benzonidazole, Imidazole-1-acetamide, N-benzyl-2-nitro-, N-Benzyl-2-nitroimidazol-1-yl-acetamide, N-benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide, N-benzyl-2-nitro-1H-imidazole-1-acetamide, NSC 299972, Radanil, Ro 07-1051, Ro 71051, Rochagan
• CAS: 22994-85-0

Descripción

Applications Benznidazole (BNZ) is traditionally used to treat Chagas disease caused by Trypanosoma cruzi. The drugs used for the treatment of this disease, Nifurtimox and Benznidazole, are toxic and present severe side effects.
References Abuin, G., et al.: Mol. Biochem. Parasitol ., 35, 229 (1989), Arora, P., et al.: J. Biol. Chem., 270, 6042 (1995), Campos, M., et al.: J. Immunol., 167, 416 (2001), Faundez, M., et al.: Antimicrob. Agents Chemother., 49, 126 (2005),

• Marca: TRC

Propiedades químicas

• Peso molecular: 260.25
• Fórmula: C₁₂H₁₂N₄O₃
• Color/Forma: Neat
• InChI: InChI=1S/C12H12N4O3/c17-11(14-8-10-4-2-1-3-5-10)9-15-7-6-13-12(15)16(18)19/h1-7H,8-9H2,(H,14,17)
• SMILES: O=C(Cn1ccnc1[N+](=O)[O-])NCc1ccccc1