Benzyl (2,2-Dimethyl-5-(4-octylphenethyl)-1,3-dioxan-5-yl)carbamate

CAS: 2514951-28-9

Ref. TR-B276205

Información del producto

• Nombre: Benzyl (2,2-Dimethyl-5-(4-octylphenethyl)-1,3-dioxan-5-yl)carbamate

Descripción

Applications Benzyl (2,2-Dimethyl-5-(4-octylphenethyl)-1,3-dioxan-5-yl)carbamate is an intermediate in the synthesis of N-[2(4-(-Octylphenyl))butanoic Acid] Fingolimod,which is an impurity of Fingolimod (F805000, HCl salt). Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.
References Brinkmann, V., et al.: Transplantation, 72, 764 (2001), Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002), Mtaloubian, M., et al.: Nature, 427, 355 (2004),

• Marca: TRC

Propiedades químicas

• Peso molecular: 481.67
• Fórmula: C₃₀H₄₃NO₄
• Color/Forma: Light Yellow Oil
• InChI: InChI=1S/C30H43NO4/c1-4-5-6-7-8-10-13-25-16-18-26(19-17-25)20-21-30(23-34-29(2,3)35-24-30)31-28(32)33-22-27-14-11-9-12-15-27/h9,11-12,14-19H,4-8,10,13,20-24H2,1-3H3,(H,31,32)
• SMILES: C[n+]1ccc(-c2ccccc2)cc1.[I-]