(2R,3R)-2,3-Bis(acetyloxy)butanedioic Acid Mono[(10S)-5-(aminocarbonyl)-10,11-dihydro-5H-dibenz[b,f]azepin-10-yl] Ester

CAS: 475674-43-2

Ref. TR-B400630

Información del producto

• Nombre: (2R,3R)-2,3-Bis(acetyloxy)butanedioic Acid Mono[(10S)-5-(aminocarbonyl)-10,11-dihydro-5H-dibenz[b,f]azepin-10-yl] Ester
• Sinónimos: (2R,3R)-2,3-diacetyloxy-4-[[(5S)-11-carbamoyl-5,6-dihydrobenzo[b][1]benzazepin-5-yl]oxy]-4-oxobutanoic acid
• Marca: TRC
• Descripción: Applications (2R,3R)-2,3-Bis(acetyloxy)butanedioic Acid Mono[(10S)-5-(aminocarbonyl)-10,11-dihydro-5H-dibenz[b,f]azepin-10-yl] Ester is an intermediate in the synthesis of Eslicarbazepine (M546510), a novel central nervous system drug.References Duncan, J., et al.: Br. J. Clin. Pharmacol., 53, 123 (2002), Almeida, L., et al.: J. Clin. Pharmacol., 45, 1062 (2005), Coppola, G., et al.: CNS Drugs, 18, 133 (2004),

Propiedades químicas

• Peso molecular: 470.43
• Fórmula: C₂₃H₂₂N₂O₉
• Color/Forma: Neat
• InChI: InChI=1S/C23H22N2O9/c1-12(26)32-19(21(28)29)20(33-13(2)27)22(30)34-18-11-14-7-3-5-9-16(14)25(23(24)31)17-10-6-4-8-15(17)18/h3-10,18-20H,11H2,1-2H3,(H2,24,31)(H,28,29)/t18-,19+,20+/m0/s1
• Clave InChI: InChIKey=LQCBRRSLDYMJSN-XUVXKRRUSA-N
• SMILES: CC(=O)O[C@@H](C(=O)O)[C@@H](OC(C)=O)C(=O)O[C@H]1Cc2ccccc2N(C(N)=O)c2ccccc21