1,3-Bis(carboxymethyl)-1H-imidazolium

CAS: 117255-11-5

Ref. TR-B415255

Información del producto

• Nombre: 1,3-Bis(carboxymethyl)-1H-imidazolium
• Sinónimos: 2-(1-(Carboxymethyl)-1H-imidazol-3-ium-3-yl)acetate

Descripción

Applications 1,3-Bis(carboxymethyl)-1H-imidazolium is an intermediate in synthesizing 1,3-Bis(2-hydroxy-2,2-diphosphonoethyl)-imidazolium Soidum Salt(Zoledronic Acid Impurity) (B443840), which is an impurity of Zolendronic Acid (trihydrate: Z623501), a biphosphonate that is used for the management of osteoporosis and the treatment of bone metastases from various types of cancers.
References Kohno, N., et al.: J. Clin. Oncol., 23, 3314 (2005); Reid, I., et al.: New Engl. J. Med., 346, 653 (2002); Rosen. L., et al.: Cancer J., 7, 377 (2000)

• Marca: TRC

Propiedades químicas

• Peso molecular: 184.15
• Fórmula: C₇H₈N₂O₄
• Color/Forma: Neat
• SMILES: O=C([O-])C[n+]1ccn(CC(=O)O)c1