1-(Boc-amino)cyclopropanecarboxylic Acid

CAS: 88950-64-5

Ref. TR-B619645

Información del producto

• Nombre: 1-(Boc-amino)cyclopropanecarboxylic Acid
• Sinónimos: 1-[[(1,1-Dimethylethoxy)carbonyl]amino]cyclopropanecarboxylic Acid, 1-(Tert-Butoxycarbonylamino)cyclopropanecarboxylic Acid, 1-[(tert-Butoxycarbonyl)amino]cyclopropanecarboxylic Acid, 1-[N-(tert-Butoxycarbonyl)amino]cyclopropanecarboxylic Acid, N-tert-Butoxycarbonyl 1-amino-1-cyclopropanecarboxylic Acid, 1-(Boc-amino)cyclopropanecarboxylic acid, 1-(Tert-Butoxycarbonylamino)cyclopropanecarboxylic acid, 1-[(2-Methylpropan-2-yl)oxycarbonylamino]cyclopropane-1-carboxylic acid, 1-[(Tert-butoxycarbonyl)amino]cyclopropanecarboxylic acid, 1-[N-(tert-Butoxycarbonyl)amino]cyclopropanecarboxylic acid, 1-[[(1,1-Dimethylethoxy)carbonyl]amino]cyclopropanecarboxylic acid, 1-[[(tert-Butoxy)carbonyl]amino]cyclopropane-1-carboxylic acid, Boc-Acpc-OH, Cyclopropanecarboxylic acid, 1-[[(1,1-dimethylethoxy)carbonyl]amino]-, N-tert-Butoxycarbonyl 1-amino-1-cyclopropanecarboxylic acid

Descripción

Applications 1-(Boc-amino)cyclopropanecarboxylic Acid is used as a reagent in the synthesis of pyrrolotriazinone derivatives as therapeutic PI3K inhibitors. Also used as a reagent in the synthesis of ether, carbamate and ester derivatives of adarotene as potential antitumor agents.
References Bernal Anchuela, F.J., et al.: PCT Int. Appl. WO 2012146666 A1 20121101. Nov 1, 2012; Giannini, G., et al.: Bioorg. Med. Chem., 20, 2405 (2012)

• Marca: TRC

Propiedades químicas

• Peso molecular: 531.619
• Fórmula: C₃₄H₃₀FN₃O₂
• Color/Forma: Neat
• InChI: InChI=1S/C34H30FN3O2/c1-40-32(39)33(25-35,37-23-27-14-6-2-7-15-27)22-31-24-38(26-36-31)34(28-16-8-3-9-17-28,29-18-10-4-11-19-29)30-20-12-5-13-21-30/h2-21,23-24,26H,22,25H2,1H3/b37-23+
• Clave InChI: InChIKey=PYICRMBSNZOUDP-GUBAARJWSA-N
• SMILES: COC(=O)C(CF)(Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)/N=C/c1ccccc1